"上海博耀生物銷(xiāo)售Phospho-PKD/PKCμ (Ser744/748) Antibody #2054，CST原裝品質(zhì)，價(jià)格優(yōu)惠，訂購(gòu)Phospho-PKD/PKCμ (Ser744/748

"上海博耀生物銷(xiāo)售Phospho-PKD/PKCμ (Ser744/748) Antibody #2054，CST原裝品質(zhì)，價(jià)格優(yōu)惠，訂購(gòu)Phospho-PKD/PKCμ (Ser744/748) Antibody #2054，詳情請(qǐng)咨詢銷(xiāo)售人員！
產(chǎn)品詳細(xì)參數(shù)如下>>>>

產(chǎn)品名稱(chēng)：Phospho-PKD/PKCμ (Ser744/748) Antibody #2054
貨號(hào)：2054
品牌：CST(cell signaling)
抗體來(lái)源：Rabbit
克隆類(lèi)型： Polyclonal
規(guī)格：

No.	Size	Price
2054P	40 ul (4 western blots)	詢價(jià)
2054S	100 ul (10 western blots)	詢價(jià)
2054L	300 ul (30 western blots)	詢價(jià)

抗體應(yīng)用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W	H M R Mk	Endogenous	115	Rabbit

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特異性/敏感度： Phospho-PKD/PKCμ (Ser744/748) Antibody detects PKD1/PKCμ only when dually phosphorylated at serines 744 and 748. This antibody may also cross-react with isoforms PKD2 and PKD3/PKCη in some species.
來(lái)源及純化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser744/748 of mouse PKD. Antibodies are purified by protein A and peptide affinity chromatography.
抗體背景：

Activation of PKC is one of the earliest events in a cascade leading to a variety of cellular responses such as secretion, gene expression, proliferation and muscle contraction (1,2). Protein kinase D (PKD), also called PKCμ, is a serine/threonine kinase whose activation is dependent on the phosphorylation of two activation loop sites, Ser744 and Ser748, via a PKC-dependent signaling pathway (3-5). In addition to the two activation loop sites, the carboxy-terminal Ser916 has been identified as an autophosphorylation site for PKD/PKCμ. Phosphorylation at Ser916 correlates with PKD/PKCμ catalytic activity (6).

關(guān)鍵詞：CST，抗體，一抗{byao_back}{byao_back2}

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