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2046 NGF Antibody #2046

會員指數: 企業(yè)認證:

價格:電議

所在地:上海

型號:2046

更新時間:2013-07-27

瀏覽次數:833

公司地址:

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產品簡介

"上海博耀生物銷售NGF Antibody #2046,CST原裝品質,價格優(yōu)惠,訂購NGF Antibody #2046,詳情請咨詢銷售人員!產品詳細參數如下

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"上海博耀生物銷售NGF Antibody #2046,CST原裝品質,價格優(yōu)惠,訂購NGF Antibody #2046,詳情請咨詢銷售人員!
產品詳細參數如下>>>>

產品名稱:NGF Antibody #2046
貨號:2046
品牌:CST(cell signaling)
抗體來源:Rabbit
克隆類型: Polyclonal
規(guī)格:
No. Size Price
2046S 100 ul (10 western blots) 詢價

抗體應用:
Applications Reactivity Sensitivity MW (kDa) Source
W H (M) Recombinant 13 Rabbit
Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特異性/敏感度: NGF Antibody detects recombinant NGF protein. It does not cross-react with other proteins.
來源及純化方法: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Thr146 of human NGF.
抗體背景:

Nerve growth factor (NGF) is a small, secreted protein and member of the neurotrophin family of growth factors that promote neuronal cell survival and differentiation (1). Producing cells release NGF that bind and activate TrkA high affinity receptors to mediate NGF-driven signaling. NGF also binds to a low affinity p75 (NTR) receptors, which belong to the death receptor family (2). Although NGF has been classically described as favoring neuron survival and differentiation, nerve growth factor can promote apoptosis in cells that contain p75 (NTR) and lack TrkA. NGF can induce neuron death in a variety of neurodegenerative conditions, including Alzheimer disease (3). Besides its neurotrophic actions, NGF has an effect on non-neuronal cells and may help mediate inflammation, angiogenesis, and stimulate breast cancer cell growth (4-6). NGF signaling is looking increasingly promising as potential drug targets for diseases.

關鍵詞:CST,抗體,一抗{byao_back}{byao_back2}

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