"上海博耀生物銷售Cleaved Lamin A (Small Subunit) (30H5) Mouse mAb #2036，CST原裝品質(zhì)，價(jià)格優(yōu)惠，訂購Cleaved Lamin A (Sma

"上海博耀生物銷售Cleaved Lamin A (Small Subunit) (30H5) Mouse mAb #2036，CST原裝品質(zhì)，價(jià)格優(yōu)惠，訂購Cleaved Lamin A (Small Subunit) (30H5) Mouse mAb #2036，詳情請(qǐng)咨詢銷售人員！
產(chǎn)品詳細(xì)參數(shù)如下>>>>

產(chǎn)品名稱：Cleaved Lamin A (Small Subunit) (30H5) Mouse mAb #2036
貨號(hào)：2036
品牌：CST(cell signaling)
抗體來源：Mouse
克隆類型： Monoclonal
規(guī)格：

No.	Size	Price
2036S	100 ul (10 western blots)	詢價(jià)

抗體應(yīng)用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
W IF-IC	H M R	Endogenous	28	Mouse IgG1

Applications Key:  W=Western Blotting  IF-IC=Immunofluorescence (Immunocytochemistry)
Reactivity Key:  H=Human  M=Mouse  R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特異性/敏感度： Cleaved Lamin A (Small Subunit) (30H5) Mouse mAb detects endogenous levels of the small fragment of lamin A (and lamin C) resulting from cleavage at aspartic acid 230. The antibody does not cross-react with full length lamin A or C.
來源及純化方法： Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to amino-terminal residues surrounding Asp230 of human lamin A.
抗體背景：

Lamins are nuclear membrane structural components that are important in maintaining normal cell functions such as cell cycle control, DNA replication, and chromatin organization (1-3). Lamin A/C is cleaved by caspase-6 and serves as a marker for caspase-6 activation. During apoptosis, lamin A/C is specifically cleaved into a large (41-50 kDa) and a small (28 kDa) fragment (3,4). The cleavage of lamins results in nuclear disregulation and cell death (5,6).

關(guān)鍵詞：CST，抗體，一抗{byao_back}{byao_back2}

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