"上海博耀生物銷(xiāo)售Cleaved Lamin A (Small Subunit) Antibody #2035，CST原裝品質(zhì)，價(jià)格優(yōu)惠，訂購(gòu)Cleaved Lamin A (Small Subun

"上海博耀生物銷(xiāo)售Cleaved Lamin A (Small Subunit) Antibody #2035，CST原裝品質(zhì)，價(jià)格優(yōu)惠，訂購(gòu)Cleaved Lamin A (Small Subunit) Antibody #2035，詳情請(qǐng)咨詢(xún)銷(xiāo)售人員！
產(chǎn)品詳細(xì)參數(shù)如下>>>>

產(chǎn)品名稱(chēng)：Cleaved Lamin A (Small Subunit) Antibody #2035
貨號(hào)：2035
品牌：CST(cell signaling)
抗體來(lái)源：Rabbit
克隆類(lèi)型： Polyclonal
規(guī)格：

No.	Size	Price
2035S	100 ul (10 western blots)	詢(xún)價(jià)

抗體應(yīng)用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IHC-P IF-IC	H M R	Endogenous	28	Rabbit

Applications Key:  W=Western Blotting  IHC-P=Immunohistochemistry (Paraffin)  IF-IC=Immunofluorescence (Immunocytochemistry)
Reactivity Key:  H=Human  M=Mouse  R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特異性/敏感度： Cleaved Lamin A (Small Subunit) Antibody detects the small fragment of lamin A (and lamin C) resulting from cleavage at aspartic acid 230 by caspase-6. The antibody does not cross-react with full length lamin A or lamin C.
來(lái)源及純化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to amino-terminal residues surrounding Asp230 in human lamin A. Antibodies are purified by protein A and peptide affinity chromatography.
抗體背景：

Lamins are nuclear membrane structural components that are important in maintaining normal cell functions such as cell cycle control, DNA replication, and chromatin organization (1-3). Lamin A/C is cleaved by caspase-6 and serves as a marker for caspase-6 activation. During apoptosis, lamin A/C is specifically cleaved into a large (41-50 kDa) and a small (28 kDa) fragment (3,4). The cleavage of lamins results in nuclear disregulation and cell death (5,6).

關(guān)鍵詞：CST，抗體，一抗{byao_back}{byao_back2}

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