產(chǎn)品簡介
"上海博耀生物銷售Phospho-Lamin A/C (Ser22) Antibody #2026,CST原裝品質(zhì),價格優(yōu)惠,訂購Phospho-Lamin A/C (Ser22) Antibody
產(chǎn)品說明
"上海博耀生物銷售
Phospho-Lamin A/C (Ser22) Antibody #2026,CST原裝品質(zhì),價格優(yōu)惠,訂購
Phospho-Lamin A/C (Ser22) Antibody #2026,詳情請咨詢銷售人員!
產(chǎn)品詳細(xì)參數(shù)如下>>>>
產(chǎn)品名稱:Phospho-Lamin A/C (Ser22) Antibody #2026
貨號:2026
品牌:CST(cell signaling)
抗體來源:Rabbit
克隆類型:
Polyclonal
規(guī)格:
| No. |
Size |
Price |
| 2026S |
100 ul (10 western blots) |
詢價 |
抗體應(yīng)用:
| Applications |
Reactivity |
Sensitivity |
MW (kDa) |
Source |
| W IF-IC |
H M R |
Endogenous |
69, 78 |
Rabbit |
Applications Key:
W=Western Blotting
IF-IC=Immunofluorescence (Immunocytochemistry)
Reactivity Key:
H=Human
M=Mouse
R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特異性/敏感度:
Phospho-Lamin A/C (Ser22) Antibody detects endogenous levels of lamin A/C only when phosphorylated at Ser22.
來源及純化方法:
Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser22 of human lamin A/C protein.
抗體背景:
Lamins are nuclear membrane structural components that are important in maintaining normal cell functions such as cell cycle control, DNA replication, and chromatin organization (1-3). Lamin A/C is cleaved by caspase-6 and serves as a marker for caspase-6 activation. During apoptosis, lamin A/C is specifically cleaved into a large (41-50 kDa) and a small (28 kDa) fragment (3,4). The cleavage of lamins results in nuclear disregulation and cell death (5,6).
關(guān)鍵詞:CST,抗體,一抗{byao_back}{byao_back2}
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