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2006 BID (7A3) Mouse mAb (Human Specific) #2006

會(huì)員指數(shù): 企業(yè)認(rèn)證:

價(jià)格:電議

所在地:上海

型號(hào):2006

更新時(shí)間:2013-07-27

瀏覽次數(shù):985

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"上海博耀生物銷售BID (7A3) Mouse mAb (Human Specific) #2006,CST原裝品質(zhì),價(jià)格優(yōu)惠,訂購(gòu)BID (7A3) Mouse mAb (Human Speci

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"上海博耀生物銷售BID (7A3) Mouse mAb (Human Specific) #2006,CST原裝品質(zhì),價(jià)格優(yōu)惠,訂購(gòu)BID (7A3) Mouse mAb (Human Specific) #2006,詳情請(qǐng)咨詢銷售人員!
產(chǎn)品詳細(xì)參數(shù)如下>>>>

產(chǎn)品名稱:BID (7A3) Mouse mAb (Human Specific) #2006
貨號(hào):2006
品牌:CST(cell signaling)
抗體來(lái)源:Mouse
克隆類型: Monoclonal
規(guī)格:
No. Size Price
2006S 100 ul (10 western blots) 詢價(jià)

抗體應(yīng)用:
Applications Reactivity Sensitivity MW (kDa) Isotype
W H Endogenous 22 Mouse IgG1
Applications Key:  W=Western Blotting
Reactivity Key:  H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特異性/敏感度: BID (7A3) Mouse mAb (Human Specific) detects endogenous levels of full length human BID.
來(lái)源及純化方法: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding the cleavage site of human BID. Antibody is supplied in HEPES buffer with 50% glycerol and less than 0.02% sodium azide.
抗體背景:

Bid is a pro-apoptotic “BH3 domain-only” member of the Bcl-2 family originally discovered to interact with both the anti-apoptotic family member Bcl-2 and the pro-apoptotic protein Bax (1). Bid is normally localized in the cytosolic fraction of cells as an inactive precursor and is cleaved at Asp60 by caspase-8 during Fas signaling, leading to translocation of the carboxyl terminal p15 fragment (tBid) to the mitochondrial outer membrane (2-4). Translocation of Bid is associated with release of cytochrome c from the mitochondria, leading to complex formation with Apaf-1 and caspase-9 and resulting in caspase-9 activation (5-7). Thus, Bid relays an apoptotic signal from the cell surface to the mitochondria triggering caspase activation (8,9).

關(guān)鍵詞:CST,抗體,一抗{byao_back}{byao_back2}

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