產(chǎn)品名：細(xì)胞表面趨化因子受體7抗體
英文名：Anti-CXCR7/RDC1
研究領(lǐng)域：細(xì)胞生物  免疫學(xué)  細(xì)胞凋亡  細(xì)胞膜受體  
抗體來源：Rabbit
克隆類型：Polyclonal
交叉反應(yīng)：Human, Mouse, Rat, Dog,
產(chǎn)品應(yīng)用：WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=3μg/Test ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量：42kDa
細(xì)胞定位：細(xì)胞膜
性    狀：Lyophilized or Liquid
濃    度：1mg/ml
免 疫 原：KLH conjugated synthetic peptide derived from human CCR7:25-59/379 <Extracellular>
亞    型：IgG
純化方法：affinity purified by Protein A
儲(chǔ) 存 液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed：PubMed

產(chǎn)品介紹
background:
The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. [provided by RefSeq, Jul 2008]

Function:
Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7.

Similarity:
Belongs to the G-protein coupled receptor 1 family.